Research Faculty

Ya-Wei Qiang, M.D., Ph.D.
Assistant Professor of Medicine

Ph.D., Department of Molecular and Tumor Pathology, Chiba University School of Medicine, Japan
M.S., Department of Hematology/Oncology, Xian Medical University, China
M.D., Xian Medical University, China
Postdoctoral fellowship, Laboratory of Cellular and Molecular Biology, National Cancer Institute, NIH, Bethesda, Maryland

Selected Publications:

1. Qiang, YW, Chen Y, Stephens O, Brown N, Chen B, Epstein J, Barlogie B, and Shaughnessy J Jr. Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma. Blood. 2008,1112(1): 196-207

2. Qiang YW, Barlogie B, Rudikoff S and Shaughnessy J Jr. Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma. Bone, 2008; 42(4): 669-80
   
   
3. Qiang YW, Shaughnessy J Jr. and Yaccoby S. Wnt3a Signaling Within Bone Inhibits Multiple Myeloma Bone Disease and Tumor Growth. Blood, 2008;112(2): 374-82
   
   
4. Qiang YW, Walsh K, Yao L, Kedei N, Blumberg P, Rubin J, Shaughnessy J Jr. and Rudikoff S. Wnts induce migration and invasion of myeloma cells via activation of RhoA and PKC pathways. Blood. 2005; 106(5): 1786-93
   
   
5. Qiang YW and Rudikoff S. Wnt signaling in B and T lymphocytes.  Front  Biosci. 2004; 9: 1000-10
   
   
6. Qiang YW, Yao L, Tosato G, Rudikoff S. Insulin-like Growth Factor I induces migration and invasion of human multiple myeloma cells. Blood. 2004; 103(1): 301-8
   
   
7. Qiang YW, Endo Y, Rubin J, Rudikoff S. Wnt Signaling in B cell Neoplasia. Oncogene. 2003; 22(10): 1536-45
   
   
8. Qiang YW, Kopantzev E, Rudikoff S. Insulin-like growth factor-I signaling in multiple myeloma: downstream elements, functional correlates and pathway cross talk. Blood.2002; 99(11): 4138-46

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