Qing Zhang, Ph.D.

Qing Zhang, Ph.D.
Assistant Professor of Medicine

Ph.D.: Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, China

Postdoctoral fellowship: Program on Bioinformatics and Systems Biology, Sanford-Burnham Medical Research Institute, San Diego, California

Selected Publications:

Zhou Y, Zhang Q, Stephens O, Heuck CJ, Tian E, Sawyer JR et al: Prediction of cytogenetic abnormalities with gene expression profiles. Blood 2012, 119: e148-e150. (co-corresponding author)

Usmani SZ, Nair B, Qu P, Hansen E, Zhang Q, Petty N et al: Primary plasma cell leukemia: clinical and laboratory presentation, gene-expression profiling, and clinical outcome with Total Therapy protocols. Leukemia 2012.

Stephens OW, Zhang Q, Qu P, Zhou Y, Chavan S, Tian E et al: An intermediate-risk multiple myeloma subgroup is defined by sIL-6r; levels synergistically increase with incidence of SNP rs2228145 and 1q21 amplification. Blood 2012, 119: 503-512.

Johnson SK, Heuck CJ, Albino AP, Qu P, Zhang Q, Barlogie B et al: The use of molecular-based risk stratification and pharmacogenomics for outcome prediction and personalized therapeutic management of multiple myeloma. Int J Hematol 2011, 94: 321-333.

Shaughnessy JD, Jr., Qu P, Usmani S, Heuck CJ, Zhang Q, Zhou Y et al: Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with Total Therapy 3. Blood 2011, 118: 3512-3524.

Zhang Q, Zmasek CM, Cai XH, Godzik A: TIR domain-containing adaptor SARM is a latest addition to the ongoing microbe–host dialog. Dev Comp Immunol 2011, 35:461-468.

Zhang Q, Zmasek CM, Godzik A: Domain architecture evolution of pattern-recognition receptors. Immunogenetics 2010, 62:263-272. [Selected by Faculty of 1000 Biology]

Zhang Q, Zmasek CM, Dishaw LJ, Mueller MG, Ye Y, Litman GW, Godzik A: Novel genes dramatically alter regulatory network topology in amphioxus. Genome Biol 2008, 9:R123. [Selected by Faculty of 1000 Biology]

Holland LZ, Albalat R, Azumi K, …, Zhang Q, …, Holland PW: The amphioxus genome illuminates vertebrate origins and cephalochordate biology. Genome Res 2008, 18:1100-1111.

Zmasek CM, Zhang Q, Ye Y, Godzik A: Surprising complexity of the ancestral apoptosis network. Genome Biol 2007, 8:R226. (co-first author) [Selected by Faculty of 1000 Biology]

Wang J, Zhang Q, Huang H, Yuan Z, Ding D, Yang S, Jiang W: Increasing synthetic performance of penicillin G acylase from Bacillus megaterium by site-directed mutagenesis. Appl Microbiol Biotechnol 2007, 74:1023-1030. (co-first author)

Cai XH, Zhang Q, Shi SY, Ding DF: Searching for potential drug targets in two-component and phosphorelay signal-transduction systems using three-dimensional cluster analysis. Acta Biochim Biophys Sin 2005, 37:293-302. (co-first author)

Wang LM, Zhang Q, Zhu W, He C, Lu CL, Ding DF, Chen ZY: Identification of the key amino acids of glial cell line-derived neurotrophic factor family receptor alpha1 involved in its biological function. J Biol Chem 2004, 279:109-116. (co-first author)

Cai XH, Zhang Q, Ding DF: Rational redesign of inhibitors of furin/kexin processing proteases by electrostatic mutations. Acta Pharmacol Sin 2004, 25:1712-1818.

Zhang Q, Wang LM, Chen ZY, Ding DF: Deducing functional epitopes for GDNF proteins and its specific GFRalpha co-receptors using phylogenetic approach. Acta Biochim Biophys Sin 2003, 35:331-337.