Professor of Medicine; Director of Basic and Translational Research; Director, Donna D. and Donald M. Lambert Laboratory of Myeloma Genetics
MSc Bar-Ilan University, Israel
Dong W, Zhang T, Epstein J, Cooney L, Wang H, Li Y, Jiang Y-B, Cogbill A, Tian Z R. Multifunctional Nanowire Bioscaffolds on Titanium. Chemistry Materials 19, 4454-4459, 2007.
Epstein J, Walker R. Myeloma and bone disease (“the dangerous tango”). Clinical Advances in Hematology and Oncology 4:300-306, 2006.
Yaccoby S, Wezeman MJ, Zangari M, Walker R, Cottler-Fox M, Gaddy D, Ling W, Saha S, Barlogie B, Tricot T, Epstein J: Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems and myelomatous SCID-hu mice. Haematologica. 2006;91:192-199.
Yaccoby S, Wezeman MJ, Henderson A, Fox MH, Yi Q, Barlogie B, Epstein J: Cancer and the microenvironment: Myeloma – osteoclast interactions as a model. Cancer Research 64:2016-2023, 2004.
Epstein J, Yaccoby S: Interactions between the bone marrow stroma and myeloma. The Hematology Journal 4:310-314, 2003.
Bhattacharyya S, Epstein J, Suva LJ, Biomarkers that discriminate multiple myeloma patients with or without skeletal involvement detected using SELDI-TOF mass spectrometry and statistical and machine learning tools. Disese Markers 2006. In press.
The bone marrow stromal environment is a major factor in myeloma cell resistance to dexamethasone.