James B. Chen, PhD

James B. Chen, Ph.D

Research Assistant Professor

Research Interest: Application of protein chip technology into predictive diagnostics of myelomachen

B.E. in Biochemistry, East China Institute of Chemical Technology, Shanghai, China

Ph.D. in Biochemistry and Molecular Biology, Louisiana State University Medical Center, New Orleans, LA

Postdoctoral Research Associate, Department of Medicine, University of Arkansas for Medical Sciences

Research Molecular Oncologist, Division of Hematology/Oncology, Arkansas Cancer Research Center, University of Arkansas for Medical Sciences

Postdoctoral Fellow, Division of Genetic Toxicology, National Center for Toxicological Research, Pine Bluff, Arkansas

Research Instructor, Department of Medicine, University of Arkansas for Medical Sciences

Selected Publications:

SM. Jazwinski, JB Chen. and J. Sun. (1993) A single gene change can extend yeast life  span: the role of Ras in cellular senescene.  Advances in Experimental Medicine &  Biology. Vol.330:45-53

James B. Chen and Joshua Epstein. (1996) Circulating clonal lymphocytes in myeloma constitute a minor subpopulation of B  cells. Blood, Vol.87:1972-1976

James B. Chen, S. Bala Dass, Dan Casciano and R.Heflich. (1998) Sensitivity of the X 174 am3  allele in relation to the  Endogenous hprt Gene for detecting of mutation in transgenic mice. Environmental and Molecular Mutagenesis, 32:229-235

R. Delonchamp, H. Malling, J. Chen and R. Heflich.(1999) An estimator of the mutant frequency in assays using transgenic animals.  Mutation Research. Mutation Research. 440   (1): 101-8

James B. Chen, Vasily N. Dobrovolsky and Robert H. Heflich. (1999) Development of a mouse embryonic fibroblast cell line containing the X 174 am3 allele as a target for detecting mutation. Mutation Research, 444: 347-353