Professor of Medicine

Associate Professor of Physiology

Education

1987   
BSc, Animal Sciences
Hebrew University of Jerusalem
Jerusalem, Israel

1999 
MSc, Animal Sciences
Hebrew University of Jerusalem

1994
PhD, Endocrinology
Hebrew University of Jerusalem

Postgraduate Training

1995  
Post-doctoral Fellowship, Physiology
Department of Physiology, University of Arkansas for Medical Sciences
Little Rock, Arkansas

1996-1999
Post-doctoral Fellowship, Multiple Myeloma
Myeloma Institute, University of Arkansas for Medical Sciences
Little Rock, Arkansas

Current Research

Dr. Yaccoby’s research is focused on the role of the microenvironment in tumor progression, metastasis and tumor cell plasticity. Using experimental myeloma models, Dr. Yaccoby’s team is growing myeloma cells from patients with MGUS and asymptomatic myeloma, with the goal of investigating the role of the microenvironment in high-risk disease and in the progression from benign disease to overt myeloma. They are characterizing specific cell type signatures in the myeloma microenvironment to better understand the interaction of myeloma cells from distinct molecular subgroups with the bone marrow microenvironment and identify patients who are likely to benefit from immunotherapy and novel drugs that target these microenvironment cells. Dr. Yaccoby’s laboratory is also working with other groups at the Myeloma Institute to identify and characterize the myeloma initiating cell using unique experimental models.

Publications

Contact Information

Email: YaccobyShmuel@uams.edu